MOL File: What is it?

Writer:   |   Revised: November 26, 2018

Microsoft Silver

MOL File Summary

File Extension MOL has three unique file types (with the primary being the MDL Molfile format) and is mostly associated with Avogadro (Open Source) and two other software programs. The majority of MOL files are considered Data Files.

MOL files are found on both mobile and desktop platforms and can be opened using Windows, Mac, and Linux operating systems. The main MOL file type has a Popularity Rating of "Low", meaning these files are not frequently present on your typical desktop or mobile device.

Although there is a lot more to know about MOL files, those are the most important details of these types of files. If you are having trouble opening these files, or would like more detailed information, please see our comprehensive information below.

Low
Universality
3128
Ranking

/ 11690

Active

File Status

26

November

2018

Page Last Updated

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MOL Types

  3 known file types use this extension

Dominant MOL File Type

.MOL
Extension:.mol
Class:MDL Molfile

MDL Molfile is a molecular data file that contains plain text information and stores information about atoms and bonds. It is used as a standard exchange format for molecular information.

Organization: Interscape
File Category:Data Files
Subkey: HKEY_CLASSES_ROOT\.mol

Software Programs That Open The MDL Molfile:


Avogadro by Open Source

Windows
Mac
Linux

Other MOL File Associations

.MOL
Extension:.mol
Class:Easy Palette Object Library

MOL file extension is used by Ulead application, photo editor for home users that is able to easy edit and share digital photos.

Organization: Ulead Systems
File Category:Data Files

Software Programs That Open Easy Palette Object Library Files:


Ulead Photo Express by Ulead Systems

Compatible with:

Windows
.MOL
Extension:.mol
Class:ModPlug Player Module List

The MOL file extension is associated with the ModPlug Player play files created using the MODPlug Tracker and other Tracking programs. This format is obsolete and no longer supported.

Organization: Open Source
File Category:Data Files

Software Programs That Open ModPlug Player Module List Files:


ModPlug Player by Open Source

Compatible with:

Windows
Mac

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MOL Demand


Top Web Browsers

Chrome (58.80%)
Firefox (11.05%)
Internet Explorer (9.04%)
Edge (8.46%)
Safari (3.87%)


MOL Troubleshooting


Frequent MOL Opening Issues

Avogadro Disappeared

You attempt to load your MOL file and get an error such as "%%os%% Can't Open The MOL File Extension". Generally, this is experienced in %%os%% because Avogadro isn't installed on your PC. Your operating system cannot associate your MOL with Avogadro, so double-clicking the file won't work.


Tip: When another MOL application is installed, you can choose to open it by selecting "Show Apps" and using that program.


Avogadro is Out-of-Date

Occasionally, you might have an outdated version of Avogadro installed that's incompatible with your MDL Molfile type. Visit the Open Source website to download (or purchase) the latest version of Avogadro. Your MDL Molfile file was probably created by a newer release of Avogadro than what's currently installed your computer.


Tip: Find clues on the correct software version by right-clicking your MOL file and clicking "Properties".


Regardless, most of the MOL file opening problems relate to not having the right version of Avogadro installed.


Associated Difficulties Loading MOL Files

Even with the correct version of Avogadro installed, you can still experience difficulties opening MOLs. There can be external issues inside of %%os%% that are causing these errors when opening MOLs. These issues include:

  • MOL file references in the Windows Registry are broken
  • Mistaken removal of the Windows registry MOL description
  • Corrupt install of Avogadro or other MOL-related program
  • Your MOL file is corrupted (issues with your MDL Molfile file itself)
  • Your MOL has adversely impacted by malware
  • Hardware associated with MOL has outdated drivers
  • Windows cannot load your MDL Molfile file due to insufficient resources (eg. RAM)

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